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Fig. 5 | Molecular Pain

Fig. 5

From: Short-term pre- and post-operative stress prolongs incision-induced pain hypersensitivity without changing basal pain perception

Fig. 5

Effect of post-surgical exposure to short-term forced swimming on post-surgical pain in male rats. a, b Mechanical stimuli. c, d Heat stimuli. e Cold stimuli. a, c, e Responses of ipsilateral (incision-stressed) paws. b, d Responses of contralateral paws. Post-surgical exposure to short-term forced swimming markedly delayed recovery in paw withdrawal threshold to mechanical stimulation (a) and paw withdrawal latencies to heat (c) and cold (e) stimuli on days 7 and 9 post-forced swimming on the ipsilateral side in the incision plus forced swimming group compared to the incision plus control group. No changes in paw withdrawal responses were seen during the observation period in the sham plus control and the sham plus forced swimming groups. Mean ± SEM. *P < 0.05, **P < 0.01 vs the corresponding time points in the incision plus control group. N = 5/group

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Molecular Pain

ISSN: 1744-8069

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