Figure 2
From: Genetic alteration of anxiety and stress-like behavior in mice lacking CaMKIV
Dark-light emergence test and Light/Dark box paradigm. a, In the dark-light emergence test, CaMKIV-/- mice (n = 7 mice) spent significantly more time outside the chamber compared to wild-type mice (n = 8 mice, t(13) = -2.65, P < 0.05,). b, In the light/dark box, no difference was seen between CaMKIV-/- and wild-type mice in the time spent in the light compartment. c, However, wild-type mice (n = 10 mice) displayed an increase in the number of light/dark transitions compared with CaMKIV-/- mice (n = 6, t(14) = 2.44, P < 0.05).