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Figure 3 | Molecular Pain

Figure 3

From: Single subject pharmacological-MRI (phMRI) study: Modulation of brain activity of psoriatic arthritis pain by cyclooxygenase-2 inhibitor

Figure 3

Similarity of brain activity for psoriatic pain in a single subject to thermal pain in a group of normal subjects. Top panel: The close proximity of brain activity is shown for the entire brain. Average group activity maps for thermal painful stimuli in 7 healthy control subjects (red) and for palpating painful joints in one patient (blue). Conjunction analysis between heat pain in healthy normal subjects and psoriatic arthritis pain indicates regions of overlap (outlined in black in lower panels), including: bilateral insula (z = -8 to +4) and thalamus (z = +4), ACC (z = 34), and right S2 region (z = +10 to +22\).

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