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Figure 3 | Molecular Pain

Figure 3

From: Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensory-nerve mitochondrial abnormalities and neuropathic pain in mice

Figure 3

Mitochondrial area distribution in fibers of saphenous nerve from WT and σ 1 R-KO mice. Mitochondrial area distribution in myelinated (a) and unmyelinated (b) fibers of saphenous nerve from control WT and σ1R-KO mice. Morphometric analysis of the mitochondrial area showed a wide range of values (<0.03 to > 0.42 μm2) in both types of nerve fiber. Each point represents the percentage of mitochondria in a particular size range. Note the absence of differences between the mitochondrial area of WT and σ1R-KO animals in either fiber type.

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Molecular Pain

ISSN: 1744-8069

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