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Figure 4 | Molecular Pain

Figure 4

From: Genetic inactivation and pharmacological blockade of sigma-1 receptors prevent paclitaxel-induced sensory-nerve mitochondrial abnormalities and neuropathic pain in mice

Figure 4

Atypical axonal mitochondria in myelinated and unmyelinated fibers of saphenous nerve of paclitaxel-treated mice. High magnification of a swollen mitochondrion with collapsed cristae at one pole, leaving a large vacuole (a). Swelling and vacuolization, with loss of cristae and disorganized matrix, are prominent in several mitochondria in myelinated (b) and unmyelinated (c) fibers. Scale Bar: 1 μm.

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Molecular Pain

ISSN: 1744-8069

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