Voltage-gated sodium channel expression in mouse DRG after SNI leads to re-evaluation of projections of injured fibers

Table 4 Changes in transcriptional levels of Na _v s in L3, L4 and L5 DRG after SNI

	% of modification (SNI/sham)			p-values of treatment (SNI) for each DRG			Overall p-value of treatment (SNI)
DRG	L3	L4	L5	L3	L4	L5
Na_v1.1	-43%	-52%	-9%	*	*	ns	p = 0.002
Na_v1.2	-30%	-34%	-34%	ns	ns	ns	p = 0.112
Na_v1.3	-27%	-9%	-38%	ns	ns	ns	p = 0.113
Na_v1.6	-32%	-42%	-11%	ns	ns	ns	p = 0.008
Na_v1.7	-35%	-16%	-16%	**	ns	ns	p < 0.001
Na_v1.8	-47%	-49%	-19%	***	***	**	p < 0.001
Na_v1.9	-27%	-37%	-29%	*	*	*	p < 0.001

% of change of Na_vs transcript in SNI as compared to sham in L3, L4 and L5 DRG independently. 2–way ANOVA with independent measures to test for overall treatment effect and post hoc Bonferroni to test for statistical significance of treatment in each DRG (*p < 0.05, **p < 0.01 and ***p < 0.001).

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