Table 1 Mature miRNAs that underwent significant differential up- or down-regulation following SNL nerve injury in HA vs. LA rats
miRNA identifier name | Mean RPM (sham pools) | Mean RPM (SNL pools) | SNL-reg subtraction method (SNL/sham fold-change) | diff-reg | qFDR   | chr. # | |||
|---|---|---|---|---|---|---|---|---|---|
|  | HA  | LA  | HA  | LA  | HA    | LA   | HA-LA   | HA-LA |  |
subtraction method, all pools | |||||||||
rno-miR-30d-5p | 9,187 | 11,047 | 8,140 | 11,168 | −0.121 (−1.129) | 0.011 (1.011) | −0.132 (0.297) | <0.001 | 7 |
rno-miR-378b | 51.6 | 47.1 | 58.6 | 33.7 | 0.125 (1.136) | −0.331 (−1.398) | 0.457 (0.533) | <0.001 | 5 |
rno-miR-322-3p | 30.7 | 29.4 | 20.8 | 32.8 | −0.384 (−1.476) | 0.109 (1.116) | −0.494 (0.592) | <0.001 | X |
added by log2 ratio method or randomization *, all pools | |||||||||
rno-miR-493-3p | 79.8 | 66.3 | 87.9 | 91.0 | 0.138 (1.102) | 0.455 (1.373) | 0.317 (0.271) | <0.001 | 6 |
rno-miR-1839-5p * | 112.1 | 108.9 | 100.3 | 129.1 | −0.110 (−1.118) | 0.168 (1.185) | −0.278 (.303) | <0.05 | 1 |
added by HA_SNL1 pool exclusion | Â | Â | Â | Â | Â | Â | Â | ||
rno-miR-125b-5p | 3,758 | 2,537 | 2,718 | 2,398 | −0.321 (−1.383) | −0.056 (−1.058) | −0.265 (0.325) | 0.002 | 8 |
rno-miR-379-5p | 201.9 | 187.5 | 188.6 | 231.6 | −0.068 (−1.071) | 0.210 1.235 | −0.278 (0.306) | 0.04 | 6 |
rno-miR-369-3p | 12.0 | 13.6 | 16.9 | 15.8 | 0.337 (1.408) | 0.148 (1.162) | 0.189 (0.246) | 0.03 | 6 |
rno-let-7f-2-3p | 11.7 | 8.1 | 10.4 | 12.8 | −0.119 (−1.125) | 0.448 (1.580) | −0.567 (0.705) | 0.03 | X |
rno-miR-340-3p | 8.9 | 11.5 | 12.6 | 9.3 | 0.346 (1.416) | −0.215 (−1.237) | 0.561 (0.653) | 0.03 | 10 |
rno-miR-6331 | 15.0 | 10.5 | 11.8 | 13.2 | −0.241 (−1.271) | 0.226 (1.257) | −0.467 (0.528) | 0.05 | 6 |