Figure 3
P2Y 6,11 receptor antagonists prevent enhanced expression of P2Y 6,11 receptors. Effect of the repeated intrathecal administration of MRS2578 (panel A) and NF340 (panel B) in spinal nerve injury-induced increase in P2Y6 and P2Y11 expression in the ipsilateral dorsal spinal cord. Data were normalized against β-actin and are expressed as the mean ± S.E.M. of 3 independent rats. * Significantly (p < 0.05) different from the naïve (N) group and # significantly (p < 0.05) different from the spinal nerve ligated (SNL) group, as determined by one-way analysis of variance followed by the Student-Newman-Keuls test.