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Figure 1 | Molecular Pain

Figure 1

From: A putative relay circuit providing low-threshold mechanoreceptive input to lamina I projection neurons via vertical cells in lamina II of the rat dorsal horn

Figure 1

VGLUT1 boutons contact spines belonging to a vertical cell. a, Projected confocal image of one of the vertical cells from the study by Yasaka et al. [6]. The dashed line represents the dorsal limit of the dense plexus of VGLUT1-immunoreactive boutons that extends ventrally from lamina IIi. The box shows the area illustrated in b and c. b, c show part of a ventral dendrite of this cell scanned to reveal Neurobiotin (green) and VGLUT1 (magenta) in a projection of 62 z-sections at 0.3 μm z-spacing. The insets are from single optical sections, and show contacts between VGLUT1 boutons and individual dendritic spines at higher magnification. They correspond to the numbered boxed areas in c, and arrowheads show the locations of the spines that receive these contacts. Scale bars: 100 μm (a), 20 μm (b,c), 5 μm (insets).

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Molecular Pain

ISSN: 1744-8069

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