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Table 4 Artn-induced changes in nAChR subunit transcription occur in the absence of TRPV1 and TRPA1 activity

From: Artemin growth factor increases nicotinic cholinergic receptor subunit expression and activity in nociceptive sensory neurons

Mouse strain

nAChRα3

nAChRβ4

nAChRβ3

 

TG

DRG

TG

DRG

TG

DRG

ART-OE

13.35*

3.99*

7.68*

2.83*

4.08*

NC

ART-OE x TRPV1−/−/TRPA1−/−

12.42*

2.36*

6.69*

2.22*

3.53*

NC

  1. Values are expressed as fold-change relative to WT ganglia. NC, not changed. Asterisk indicates significant difference with p < 0.05.
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Molecular Pain

ISSN: 1744-8069

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