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Figure 3 | Molecular Pain

Figure 3

From: Spinal 5-HT3 receptors mediate descending facilitation and contribute to behavioral hypersensitivity via a reciprocal neuron-glial signaling cascade

Figure 3

5-HT 3 A receptor expression in spinal dorsal horn neurons. A. Distribution of 5-HT3A receptor expression in the spinal dorsal horn under low magnification. Intense expression of 5-HT3A receptor immunoreactivity was mainly observed in the superficial layers of the spinal dorsal horn. B. Double immunostaining showing 5-HT3A receptor profiles also labeled with NeuN, a neuronal marker in the dorsal horn cells (arrows), from the inset of A. C. Colocalization of immunoreactivity of 5-HT3A receptor and fractalkine in the spinal dorsal horn cells. Arrows indicate examples of double-labeled profiles. Scale bar = 100 μm (A) and 25 μm (B and C).

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Molecular Pain

ISSN: 1744-8069

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