Skip to main content
Figure 1 | Molecular Pain

Figure 1

From: Activated spinal astrocytes are involved in the maintenance of chronic widespread mechanical hyperalgesia after cast immobilization

Figure 1

Time courses of the changes in mechanical and heat hyperalgesia in chronic post-cast pain (CPCP) rats. (A–D) Time courses of the changes in mechanical pain threshold in the bilateral calf skin (A), calf muscle (B), hindpaws (C), and both sides of the tail (D) after cast removal (n = 6). (E) Time course of the change in heat withdrawal latency in both hindpaws (n = 11). The horizontal axis indicates measurement time points (B: before cast, 2 h: 2 hours, 1 d: 1 day, w: weeks). Data are presented as the mean ± SEM. One-way ANOVAs and Dunnett’s post hoc tests identified significant threshold changes in all tested body parts after cast removal. *p < 0.05, compared with B value.

Back to article page

Molecular Pain

ISSN: 1744-8069

Contact us