Figure 5From: The prophylactic effects of a traditional Japanese medicine, goshajinkigan, on paclitaxel-induced peripheral neuropathy and its mechanism of action Comparison of the expressions of TRPV4, integrin, and Src tyrosine kinase by tissue microarray. In PTX group, TRPV4, integrin, and Src tyrosine kinase were more strongly expressed in the nucleus, cytoplasm, and cell membrane in ganglion cell compared with the control group. In PTX + GJG group, no clear change in the expression of Src tyrosine kinase and integrin was noted, but the expression of TRPV4 in the nucleus and cytoplasm was clearly decreased compared with PTX group.Back to article page