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Figure 2 | Molecular Pain

Figure 2

From: HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors

Figure 2

Expression of acetyl-H3 and acetyl-H4 in the mouse dorsal root ganglia after a 3-day curcumin pretreatment. Repeated injection of curcumin (100 mg/kg, ip, for three days) reduced the expression of acetyl-H3 and acetyl-H4 in the DRG. DRGs were dissected on the third day, 24 hours after the last administration. A representative immunoblot of acetylated-H3 and acetylated-H4 in DRG extracts from mice treated with curcumin is shown in (A) and (B) respectively. Densitometric analysis of acetyl-H3 and acetyl-H4 normalized by actin is shown. Data are the means ± S.E.M. of 4 animals. *p < 0.05 (Student’s t test) versus values obtained in animals treated with vehicle.

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Molecular Pain

ISSN: 1744-8069

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