No association of polymorphisms in the serotonin transporter gene with thermal pain sensation in healthy individuals

Table 1 Demographic and clinical characteristics of participants

	Low 5-HTT expression	High 5-HTT expression	P-value
Demographic characteristics
N (men:women)	40 (21:19)	40 (20:20)	0.82^a
Age, mean ± SD (minimum-maximum), year	25 ± 2.3 (19–31)	25 ± 2.4 (19–32)	0.67^a
Clinical data
Major depression inventory (MDI)
MDI score mean ± SD (minimum-maximum)	5.5 ± 3.0 (0–13)	5.3 ± 3.1 (0–13)	0.74^a
Moderate or severe depression, N	0	0
General anxiety disorder (GAD)
GAD score mean ± SD (minimum-maximum)	3.1 ± 2.9 (0–13)	3.1 ± 2.2 (0–7)	0.93^a
Doubtful anxiety disorder	2	0

^a t-test.
MDI scores: 0–21 = “no depression”, 26–30 = “moderate depression”, 31 or more = “severe depression”.
GAD scores: 0–7 = ” no anxiety disorder”, 8–14 = ” doubtful anxiety disorder”, 15–19 = ” mild anxiety disorder”, 20–29 = ” moderate anxiety disorder”, 30–50 = ” severe anxiety disorder”.

ISSN: 1744-8069