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Figure 6 | Molecular Pain

Figure 6

From: The effects of protein phosphatase inhibitors on the duration of central sensitization of rat dorsal horn neurons following injection of capsaicin

Figure 6

Rate histograms show the responses of a dorsal horn neuron to mechanical stimuli, the effect of fostriecin perfusion before capsaicin injection and the changes following intradermal injection of capsaicin. Top row: baseline background activity and responses to brush, press, and pinch. Second row: lack of effect of fostriecin infusion (3 μM) within the dorsal horn. The panels below indicate the effects of the injection of capsaicin after fostriecin infusion: at 30 min after capsaicin injection (Third row); at 1 h after capsaicin injection (Fourth row); at 2 h after capsaicin injection (Fifth row) and 3 h after capsaicin injection (Bottom row). Horizontal lines above responses in the top row indicate when the stimuli were applied.

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