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Figure 2 | Molecular Pain

Figure 2

From: Genetic reduction of chronic muscle pain in mice lacking calcium/calmodulin-stimulated adenylyl cyclases

Figure 2

Behavioral nociceptive responses to intramuscular formalin in AC1 and AC8 single KO mice. Cumulative response for each 5 minutes time is plotted on y axis as duration of responses. A. Comparison of nociceptive responses to intramuscular formalin in wild-type and AC1 KO mice. Wild-type, n = 4 mice; AC1 KO, n = 8 mice. B. Data from experiment A is grouped as early, intermediate and late phases in comparison with wild-type mice. p < 0.05. *Significant difference from wild-type mice. C. Comparison of nociceptive responses to intramuscular formalin in wild-type and AC8 KO mice. Wild-type, n = 4 mice; AC8 KO, n = 8 mice. D. Data from experiment C is grouped as early, intermediate and late phases in comparison with wild-type mice.

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