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Table 4 Association of four ADRA2C markers with movement scores in sciatica patients

From: Do motor control genes contribute to interindividual variability in decreased movement in patients with pain?

dbSNP ID

Allele1

Allele2

Genotype

Count

Movement Score

p Value*

rs13118771

T

C

1/1

253

11.22

0.0267

   

1/2

53

10.16

 
   

2/2

4

9.87

 

rs6846820

A

G

1/1

6

9.19

0.0182

   

1/2

51

10.26

 
   

2/2

253

11.23

 

rs7434444

C

G

1/1

16

11.63

0.4313

   

1/2

139

11.13

 
   

2/2

155

10.88

 

rs7678463

C

G

1/1

6

9.35

0.2490

   

1/2

74

10.84

 
   

2/2

230

11.12

 

Haplotype analysis

No. of haplotype 2121 (CAGC)

  
   

2

3

9.3

0.0216

   

1

52

10.2

 
   

0

255

11.2

 
  1. p values shown are for additive model, which assumes that each copy of the uncommon allele alters the movement score by a similar amount, and uncorrected for examining 121 SNPs in 22 haplotype blocks in 14 genes.
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Molecular Pain

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