Figure 1From: Marked attenuation of inflammatory mediator-induced C-fiber sensitization for mechanical and hypotonic stimuli in TRPV4-/- miceThe average time course of the response of C-fibers during the 60 sec period after injection of simplified inflammatory soup was not significantly different in TRPV4+/+ and TRPV4-/- mice (unpaired t-test, p > 0.05). The bin width is 1 sec. A. The open bars represent activity evoked by simplified inflammatory soup in TRPV4+/+ C-fibers (n = 11), and B. The filled bars represent action potentials evoked in TRPV4-/- C-fibers (n = 13).Back to article page