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Figure 3 | Molecular Pain

Figure 3

From: Marked attenuation of inflammatory mediator-induced C-fiber sensitization for mechanical and hypotonic stimuli in TRPV4-/- mice

Figure 3

Upper panel, response of a TRPV4+/+ C-fiber to hypotonic solution 15 min after injection of simplified inflammatory soup. Arrow indicates the time of injection of hypotonic solution. Lower panel, the average time course of the response of C-fibers during the first 60 sec after injection of hypotonic solution in TRPV4+/+ mice (open bar, n = 11). The bin width is 1 sec. B. Upper panel, response of a TRPV4-/- C-fiber to hypotonic solution after injection of simplified inflammatory soup. Lower panel, the average time course of the response of C-fibers during the first 60 sec after injection of hypotonic solution in TRPV4-/- mice (filled bars, n = 9).

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Molecular Pain

ISSN: 1744-8069

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