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Figure 3 | Molecular Pain

Figure 3

From: Phosphorylation of ERK in neurokinin 1 receptor-expressing neurons in laminae III and IV of the rat spinal dorsal horn following noxious stimulation

Figure 3

pERK and NK1r following noxious thermal stimulation or formaldehyde injection. Confocal images that show immunoreactivity for pERK (a,c) and NK1r (b,d) in parasagittal sections of the left dorsal horn following immersion of the hindpaw in water at 52°C (a,b) or injection of 2% formaldehyde (c,d). In each case there is a single large lamina III NK1r-immunoreactive neuron that is also pERK-positive, and there is internalisation of the receptor on its dorsal dendrites (arrows). The images are projections of 11 (a,b) or 8 (c,d) optical sections at 2 μm z-spacing. Scale bar = 50 μm.

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Molecular Pain

ISSN: 1744-8069

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