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Figure 2 | Molecular Pain

Figure 2

From: Activation of the neurokinin-1 receptor by substance P triggers the release of substance P from cultured adult rat dorsal root ganglion neurons

Figure 2

The immunocytochemical localization of the neurokinin-1 receptor and SP in cultured adult rat DRG cells. The time-dependent expression of the neurokinin-1 receptor (A) and SP (B) in cultured DRG neurons divided into three groups: control group (i-iv), 200 pg/dish SP group (v-viii) and 200 pg/dish SP plus 1 μM CP-96,345 group (ix-xii). Photomicrographs were taken with the Olympus IX71 inverted microscope (x40). The arrows indicate the neurokinin-1 receptor- or SP-positive neurons (brown). The red arrows indicate the DRG neurons where the neurokinin-1 receptors are not expressed in their membrane. Scale bars: 20 μm.

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Molecular Pain

ISSN: 1744-8069

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