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Table 1 Diplotypes and their frequencies for each of nine genotypes at two SNPs, and composite diplotypes for one assumed sex-specific risk haplotype chosen from four possible haplotypes.

From: A computational model for sex-specific genetic architecture of complex traits in humans: Implications for mapping pain sensitivity

  Diplotype Risk Haplotype in Males Risk Haplotype in Females
Genotype Configuration Male Freq. Female Freq. [11] [10] [01] [00] [11] [10] [01] [00]
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  1. Two alleles for each of the two SNPs are denoted as 1 and 0, respectively. Genotypes at different SNPs are separated by a slash. Diplotypes are the combination of two bracketed maternally and paternally derived haplotypes. By assuming different haplotypes as a risk haplotype (denoted as A for males and B for females), composite diplotypes are accordingly defined and their genotypic values are given.