Figure 3
Alteration of TTX-R and TTX-S Na+ current densities in slow and fast small DRG neurons after CCD and CCI treatment. A, B, H and I: Examples of the TTX-R and TTX-S currents recorded with the prepulse inactivation protocol with 40 ms to -10 mV test pulse in the slow neurons (A and B) and the fast neurons (H, I) from CCD, CCI and control DRGs, respectively. C, D, J and K: Alterations of the TTX-R and TTX-S current densities in the slow (C and D) and the fast (J and K) neurons. E, F, L and M: Distribution of the TTX-R and TTX-S current densities in the slow (E and F) and the fast (L and M) neurons. The densities were binned and plotted against neuron number (%). G and N: Input capacitance (Cm) of the slow (G) and fast (N) neurons from control, CCD and CCI groups. *, p < 0.05 and **, p < 0.01 indicate significant differences compared with the control group. #, p < 0.05 indicate significant differences compared with CCI group.