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Table 4 Effect of sciatic nerve block on BDNF-IR expression at 1 h after incision

From: Brain derived neurotrophic factor (BDNF) contributes to the pain hypersensitivity following surgical incision in the rats

 

OD of BDNF-IR in the dorsal horn

Percentage of BDNF-IR neurons

 

Sham

Saline

Lidocaine

Sham

Saline

Lidocaine

Contra

0.19 ± 0.03

0.25 ± 0.04

0.24 ± 0.05

12.8 ± 1.8

14.3 ± 1.9

14.2 ± 1.5

Ipsi

0.20 ± 0.04

0.46 ± 0.09*#

0.18 ± 0.04

13.4 ± 2.1

33.2 ± 4.6*#

13.6 ± 0.8

  1. *p < 0.05 vs contralateral side, #p < 0.05 vs sham-operated group, † p < 0.05 vs saline injection