Proteomic profiling of neuromas reveals alterations in protein composition and local protein synthesis in hyper-excitable nerves

Table 1 Numbers of protein spots differentially expressed between 3 day, 1 week, 2 week, 3 week and 2 week plus 3 week neuromas and control saphenous nerves.

	3 day neuroma/control	1 week neuroma/control	2 week neuroma/control	3 week neuroma/control	2 and 3 week neuroma/control
Total number of differentially expressed spots (≥1.75-fold)	224	248	254	182	218
Increased	137	141	153	125	138
Decreased	87	109	101	57	80

Spots displaying a ≥1.75-fold increase or decrease in expression with a Student T-test P value of ≤ 0.05 (n = 3/4) and matching across all 8 analytical gels were included.

ISSN: 1744-8069