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Figure 1 | Molecular Pain

Figure 1

From: Descending serotonergic controls regulate inflammation-induced mechanical sensitivity and methyl-CpG-binding protein 2 phosphorylation in the rat superficial dorsal horn

Figure 1

Time course of P-MeCP2 expression in the superficial dorsal horn after CFA injection. CFA injection in the hind paw significantly increased MeCP2 phosphorylation in the superficial dorsal horn, ipsilateral to the injection. Changes in P-MeCP2 expression were seen exclusively in Lamina I and II, with the exception of expression in Lamina 3 to 4 at 6 h. Data show mean ± standard error of the mean. *P < 0.05, **P < 0.001, ***P < 0.0001, always vs naïve within the same dorsal horn area.

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