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Figure 6 | Molecular Pain

Figure 6

From: Descending serotonergic controls regulate inflammation-induced mechanical sensitivity and methyl-CpG-binding protein 2 phosphorylation in the rat superficial dorsal horn

Figure 6

Intrathecal 5,7-DHT causes serotonin depletion but no glial proliferation or cell death. Tissue was taken 7 days after 5,7-DHT treatment and dorsal horn sections were stained for 5-HT, GFAP and NeuN. 5-HT staining confirmed a complete depletion of 5-HT in the superficial dorsal horn 7 days after 5,7-DHT, and GFAP and NeuN staining indicated that, at the concentration used in this study, 5,7-DHT did not cause glial proliferation or hypertrophy or abnormal cell death. Scale bar, 50 ÎĽm.

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Molecular Pain

ISSN: 1744-8069

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