Figure 2From: Differential regulation of morphine antinociceptive effects by endogenous enkephalinergic system in the forebrain of miceComparison of nociceptive behavioural responses and the antinociceptive effect of morphine in WT and KO mice. Results from the von Frey test (A) tail withdrawal test (B), EMG evoked by incremental laser pulse duration (C), and hot plate test (D) are shown. The analgesic effects of morphine (5 mg/kg and 10 mg/kg) on the hot plate test as a function of time (E) and 40 min after morphine administration are also shown (F).Back to article page