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Figure 3 | Molecular Pain

Figure 3

From: Functional identification of NR2 subunits contributing to NMDA receptors on substance P receptor-expressing dorsal horn neurons

Figure 3

The NMDA g(-90 mV)/g(MIC) ratio is not a function of the amplitude of NMDA-evoked membrane current. (A) The g(-90 mV)/g(MIC) ratio was calculated for each test ramp throughout NMDA applications in the absence and presence of antagonists and plotted as a function of NMDA-evoked current amplitude. (B) Summary of the antagonist effects on the g(-90 mV)/g(MIC) ratio. (C) The VMIC was calculated for each test ramp throughout NMDA applications in the absence and presence of antagonists and plotted as a function of NMDA-evoked current amplitude for the same data as (A). (D) Summary of the antagonist effects on the VMIC (n = 15). (E) The same data as in (B) but grouped according to the sequences of drug application.

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Molecular Pain

ISSN: 1744-8069

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