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Figure 4 | Molecular Pain

Figure 4

From: Distinct expression of synaptic NR2A and NR2B in the central nervous system and impaired morphine tolerance and physical dependence in mice deficient in postsynaptic density-93 protein

Figure 4

Formalin-induced licking behaviors on day 1 after morphine withdrawal in WT and KO mice that received subcutaneous injections of 20 mg/kg morphine (M) or saline (S) twice daily for 6 days. (A) Time course of formalin-induced licking behaviors. *P < 0.05 or **P < 0.01 vs the values in the saline-treated WT mice at the corresponding time point. (B) Summary of licking duration in the first and second phases. **P < 0.01 vs the saline-treated WT mice in the second phase.

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Molecular Pain

ISSN: 1744-8069

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