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Figure 1 | Molecular Pain

Figure 1

From: Involvement of LPA1 receptor signaling in the reorganization of spinal input through Abeta-fibers in mice with partial sciatic nerve injury

Figure 1

Lack of Aβ-fiber stimulation-induced ERK activation in Lpar1-/- mice after nerve injury. (A-H) Representative pictures of pERK signals in the ipsilateral spinal dorsal horn after the Aβ-fiber stimulation (2000 Hz) to the right hind paw (see Methods). Arrows in (D) indicate Aβ-fiber stimuli-specific pERK signals observed in wild-type nerve-injured mice. M: medial, L: lateral, D: dorsal, V: ventral. (I) Number of pERK-positive cells per section in ipsilateral dorsal horn. *:p < 0.05 vs. sham, #:p < 0.05 vs. wild-type (WT). Data represent the means ± S.E.M. from experiments using 4–6 mice.

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Molecular Pain

ISSN: 1744-8069

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