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Figure 3 | Molecular Pain

Figure 3

From: The role of TRPV1 in different subtypes of dorsal root ganglion neurons in rat chronic inflammatory nociception induced by complete Freund's adjuvant

Figure 3

Double immunofluorescent staining of TRPV1 in DRG with neuronal markers of three subtypes at day 3 as an example. A, with NF200. In control animals, rare double staining of TRPV1 with NF200 was seen; after CFA injection, double staining of TRPV1 with NF200 significantly increased. B, with CGRP. Double staining of TRPV1 with CGRP significantly increased in CFA rats. C, with IB4. In control animals, double staining of TRPV1 with IB4 was ~50%; after CFA injection, double staining with IB4 significantly increased. Arrows indicate the doubly-labeled staining. Scale bar: 50 μm.

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