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Figure 4 | Molecular Pain

Figure 4

From: Role of spinal cord alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors in complete Freund's adjuvant-induced inflammatory pain

Figure 4

The relative levels of GluR2 (A and B) and GluR1 (C and D) in the crude cytosolic (A and C) and plasma membrane fractions (B and D) from the ipsilateral L 4–5 dorsal horn at 2 and 24 h following saline or CFA injection. Naïve rats (n = 4–8) were used as a control group. Data are presented as mean ± SEM. n = 4–8 rats/treatment. * p < 0.05, ** p < 0.01 vs the corresponding naïve group. E: The specificity of the fractionation procedure. Top: representative Western blots showing the expression of N-cadherin, PSD-95, and β-actin in total soluble fraction, plasma membrane fraction, and cytosolic fraction from L4–5 dorsal horns of naïve rats (n = 3). Bottom: statistical summary of the densitometric analysis expressed relative to the corresponding protein levels in the total soluble fraction.

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Molecular Pain

ISSN: 1744-8069

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