Skip to main content
Figure 7 | Molecular Pain

Figure 7

From: High concentrations of morphine sensitize and activate mouse dorsal root ganglia via TRPV1 and TRPA1 receptors

Figure 7

Morphine sensitizes CGRP-release stimulated by noxious heat. Release of CGRP from isolated hindpaw skin of mice stimulated by noxious heat of 47°C applied for 5 min (open symbols). The contralateral hindpaw skin flap of every animal was exposed to 47°C in the presence of 310 μM morphine (closed symbols) which slightly facilitated the release of CGRP stimulated by heat (n = 7). The inset shows the results with and without morphine for every animal. *p < 0.05.

Back to article page

Molecular Pain

ISSN: 1744-8069

Contact us