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Figure 2 | Molecular Pain

Figure 2

From: Behavioural and electrophysiological characterisation of experimentally induced osteoarthritis and neuropathy in C57Bl/6 mice

Figure 2

Behavioural nociception in MIA-injected mice. A. Development of mechanical hypersensitivity in MIA-injected mice. Graph depicts the changes in mechanical force required to elicit a paw withdrawal in response to a mechanical stimulus for the ipsilateral and contralateral hindpaws of MIA-injected mice (n = 18; day 28 n = 4) and the ipsilateral hindpaws of saline-injected mice (n = 16; day 28 n = 4). 50% paw withdrawal thresholds (PWT) are expressed as mean ± S.E.M. * denotes significant differences of ipsilateral MIA v ipsilateral saline; denotes significant differences of MIA ipsilateral v MIA contralateral. 3 symbols, p < 0.001; 2 symbols, p < 0.01; 1 symbol, p < 0.05. 2B. Lack of development of thermal hypersensitivity in MIA-injected mice. Graph depicts the time taken to elicit paw withdrawal in response to a noxious thermal stimulus for the ipsilateral and contralateral hindpaws of MIA-injected mice (n = 11) and the ipsilateral hindpaws of saline-injected mice (n = 11).

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Molecular Pain

ISSN: 1744-8069

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