Figure 4
From: Antidepressants inhibit P2X4 receptor function: a possible involvement in neuropathic pain relief
Effect of intrathecal administration of paroxetine on the decrease in the PWT after nerve injury. A significant antiallodynic effect was observed following intrathecal administration of paroxetine at doses of 3 nmol and 10 nmol at day 7 (a), and 3 nmol at day 14 (b) after nerve injury (**p < 0.01 and *p < 0.05; paroxetine 3 nmol vs. control, #p < 0.05; paroxetine 10 nmol vs. control by a Dunn's multiple comparison test after a Kruskal-Wallis test). Data are means ± SEM of 5–8 rats.