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Figure 3 | Molecular Pain

Figure 3

From: Minocycline treatment inhibits microglial activation and alters spinal levels of endocannabinoids in a rat model of neuropathic pain

Figure 3

Effects of chronic intraperitoneal dosing of minocycline (Mino, 30 mg/kg) or vehicle (Veh, sterile water) on the levels of endocannabinoids (A, B) and related fatty acid ethanolamides (C, D) in the ipsilateral spinal cord of spinal nerve ligated (SNL) or sham-operated rats. Data were analysed using Mann-Whitney nonparametric test and are expressed as a mean percentage of contralateral levels ± SEM (n = 5 – 6 rats/group). * P < 0.05, ** P < 0.01 vs contralateral paw. AEA, anandamide; 2-AG, 2-arachidonoylglycerol; PEA, N-palmitoylethanolamine; OEA, N-oleoylethanolamine.

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