Figure 6

Effects of systemic injection of pregabalin on the evoked neuronal responses to mechanical stimulation of the peripheral receptive field. Pregabalin produced significant inhibition of dynamic brush and mechanical punctate evoked neuronal responses in the MIA treated group (n = 9) compared with pre-drug baseline responses. The drug produced little or no effect in the sham control group (n = 8). Data are expressed as the mean percentage of pre-drug control values ± S.E.M. * p < 0.05 significant difference compared with pre- drug baseline control data.