Skip to main content
Figure 1 | Molecular Pain

Figure 1

From: Roles of the AMPA receptor subunit GluA1 but not GluA2 in synaptic potentiation and activation of ERK in the anterior cingulate cortex

Figure 1

Abolishment of cingulate potentiation in GluA1-/- mice. (A) Diagram of a slice showing the placement of a whole-cell patch recording and a stimulation electrode in the ACC. (B) These traces showing typical voltage responses to current injections of -100, 0, and 100 pA in ACC neurons from WT and GluA1-/- mice. (C) LTP was induced in ACC pyramidal neurons in WT mice (n = 13 slices/6 mice). (D) LTP was lost in ACC pyramidal neurons in GluA1-/- mice (n = 8 slices/6 mice). (C-D) The insets show averages of five EPSCs at baseline responses and 30 min after the pairing procedure (arrow). The dashed line indicates the mean basal synaptic responses.

Back to article page

Molecular Pain

ISSN: 1744-8069

Contact us