Table 1 Summary of basic electrophysiological properties for ACC neurons in wild-type and GluA1 and GluA2 knockout mice
WT | GluA1 -/- | WTCD1 | GluA2 -/- | |
|---|---|---|---|---|
Resting membrane Potential (mV) | 68.3 ± 0.8 | 68.0 ± 1.0 | 67.8 ± 1.0 | 68.5 ± 0.8 |
Input resistance (MΩ) | 113.5 ± 5.4 | 112.4 ± 5.0 | 130.3 ± 6.9 | 154.8 ± 14.0 |
Frequency (Hz) | 4.6 ± 0.5 | 4.0 ± 0.4 | 4.6 ± 0.3 | 4.4 ± 0.5 |
AP amplitude (mV) | 93.8 ± 5.5 | 94.8 ± 5.0 | 102.3 ± 1.5 | 103.5 ± 1.9 |
AP Half-width (ms) | 2.3 ± 0.2 | 2.3 ± 0.3 | 1.9 ± 0.1 | 1.8 ± 0.1 |
AHP amplitude (mV) | 10.0 ± 2.0 | 8.8 ± 1.6 | 7.7 ± 0.5 | 7.0 ± 0.7 |