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Table 1 Differential effects of 35 μM wortmannin treatment on P2X3 current amplitude (%) in DRG neurons and recombinant expression systems.

From: Subtype-specific regulation of P2X3 and P2X2/3 receptors by phosphoinositides in peripheral nociceptors

 

Control

Wortmannin

DRG neurons

100.0 ± 9.3

20.4 ± 4.2 ***

HEK293 cells

100.0 ± 9.2

107.6 ± 21.0

Xenopus oocytes

92.8 ± 6.3

94.2 ± 12.2

  1. *** P < 0.001
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Molecular Pain

ISSN: 1744-8069

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