Skip to main content
Figure 7 | Molecular Pain

Figure 7

From: Tumor necrosis factor-alpha (TNF-α) enhances functional thermal and chemical responses of TRP cation channels in human synoviocytes

Figure 7

TNF-α induces TRPV1 and TRPV4 gene expression increases in synoviocytes. The SW982 cells when stimulated with 1 ng/ml TNF-α had increased TRPV1 and TRPV4 gene expression levels over time. The cells were harvested at 0, 4, and 8 hr for RNA extraction and analysis using quantitative RT-PCR analysis. Relative expression was compared to controls normalized at the same time point and assigned a value of 1. Each PCR reaction was normalized to the β-actin internal control. * indicates a statistically significant difference (p < 0.05) tested by ANOVA on ranks.

Back to article page

Molecular Pain

ISSN: 1744-8069

Contact us