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Figure 2 | Molecular Pain

Figure 2

From: Modulation of transient receptor potential vanilloid 4-mediated membrane currents and synaptic transmission by protein kinase C

Figure 2

Sensitization of TRPV4 and TRPV1 by PKC in cultured DRG neurons. A. Both capsaicin (100 nM)-induced and 4α-PDD (10 μM)-induced currents are potentiated by a PKC activator, PDBu (1 μM). B, C. Summary graphs showing potentiation of 4α-PDD- and capsaicin-induced current activity by PDBu (1 μM; n = 11). The asterisk (*) represents P < 0.05 as compared to control.

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