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Figure 9 | Molecular Pain

Figure 9

From: Nociception-induced spatial and temporal plasticity of synaptic connection and function in the hippocampal formation of rats: a multi-electrode array recording

Figure 9

Showing stimulus intensity-network response functional curves in the hippocampal formation of saline (Sal-control) and formalin (F)-inflamed rats. A, an example showing the individual field excitatory postsynaptic potentials (fEPSPs) in either the dentate gyrus (DG) (upper) or the CA1 (lower) area of Sal-control and F-inflamed slices. Input/output relationships of stimulus intensity versus amplitude (B) or (C) slope of DG- (upper) and CA1 (lower) fEPSP were constructed. Note the formalin-induced significant leftward shift of input/output curves for fEPSP amplitude and slope. Vertical scale in A indicates amplitude of the potentials, while horizontal scale indicates time sweep. The number of slices for each group is shown in parentheses. Error bars: ± S.E.M.

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