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Figure 4 | Molecular Pain

Figure 4

From: Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain

Figure 4

LPA induces ATX-mediated LPA production through the LPA 3 receptor in vitro. (a) Schematic representation of the method used. Details are described in the text. (b) Quantification of LPA production by LPA (0.1 pmol)-treated culture media with or without recombinant ATX (rATX, 30 ng/ml). The capital letter "C" showed in the time course axis represents the vehicle group. (c) LPA3 receptor-dependent LPA production by LPA and rATX. All data represent the mean ± SEM from three to seven separate experiments. *p < 0.05 compared with the vehicle or WT group. Other details are shown in the legend of Figure 1.

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Molecular Pain

ISSN: 1744-8069

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