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Figure 4 | Molecular Pain

Figure 4

From: Upregulation of casein kinase 1ε in dorsal root ganglia and spinal cord after mouse spinal nerve injury contributes to neuropathic pain

Figure 4

CK1ε expression in the DRG neurons after spinal nerve injury. (A-C) Immunofluorescent micrographs showing CK1ε-positive neurons in L5 DRG sections from sham- (A) and SNL- (B) operated C57BL/6J mice, and SNL-operated Ca v 2.2-/- mice (C). Scale bar, 50 μm. (D, E) Percentages (D) and immunofuorescence intensities (E) of CK1ε-positive neurons in the DRGs. DRG neurons were divided into small-sized (< 600 μm2), medium-sized (600-1200 μm2), and large-sized (> 1200 μm2) groups based on their cross-sectional areas. *p < 0.05, ***p < 0.001 (one-way ANOVA followed by Tukey's post hoc test). n = 12.

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