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Figure 8 | Molecular Pain

Figure 8

From: Ryanodine receptors contribute to the induction of nociceptive input-evoked long-term potentiation in the rat spinal cord slice

Figure 8

Increase in mEPSCs frequency by caffeine in superficial dorsal horn neurons. A, Sample traces of mESPCs recorded from a lamina II neuron in the presence of 0.5 μM TTX before (left) and after bath application of 10 mM caffeine for about 5 min (right). B. A histogram shows the time course of changes in mEPSCs frequency before, after and following washout of 10 mM caffeine in the presence of 0.5 μM TTX in an individual neuron. C and D, The averaged frequency and amplitude for all cells treated with 10 mM caffeine (n = 16; 5 s bins) in the presence of 0.5 μM TTX. Membrane potential was clamped at -70 mV. Error bars represent s.e.m. n: the number of cells.

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Molecular Pain

ISSN: 1744-8069

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