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Figure 7 | Molecular Pain

Figure 7

From: Cannabinoid-mediated modulation of neuropathic pain and microglial accumulation in a model of murine type I diabetic peripheral neuropathic pain

Figure 7

Tactile (A) and thermal (B) sensory testing data for mice with established diabetes receiving either intranasal or intraperitoneal cannabidiol or SR144528 at low high dose, with comparison to non-diabetic mice receiving intranasal or intraperitoneal saline. There were no effects upon either tactile allodynia or thermal hyperalgesia development or maintenance in any group at any dose (non-matched ANOVA tests, p NS). [n = 4-10 mice in each mouse cohort for each time point] despite early intervention studies for cannabidiol demonstrating protection against development and maintenance of neuropathic pain.

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Molecular Pain

ISSN: 1744-8069

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