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Figure 6 | Molecular Pain

Figure 6

From: Long lasting pain hypersensitivity following ligation of the tendon of the masseter muscle in rats: A model of myogenic orofacial pain

Figure 6

Immunofluorescence staining of phosphoserine896-NR1 (P-NR1), GFAP and CD11b in naive and TASM-ligated (TL) rats. a. Note increased immunostaining at 3 d and 2w after tendon ligation, suggesting NMDA receptor activation and glial hyperactivity. Scale = 0.025 mm. b. Localization of P-NR1 in Vc neurons at 3 d after tendon ligation. P-NR1 is shown as green fluorescence (Alexa Fluor 488, left). NeuN is visualized with Cy3 (red, middle). Overlap of left and middle panels reveals cells that exhibit double fluorescence of NeuN (nucleus) and P-NR1 (cytoplasm) in the same neurons (right). Examples of double-labeled neurons are indicated by arrows. Scale = 0.05 mm

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Molecular Pain

ISSN: 1744-8069

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